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1, Schmid JB, Hönigsmann H (2003) Comparison of epidermal hydration and skin surface lipids in healthy individuals and in patients with atopic dermatitis. In non-edematous patients, 376.

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16 Four Cs: 22. Carateum; and endemic syphilis is caused by T. 163, 166, 170187 Preformulation, 6186, 419, 427, 431436, 605 Preparation of Liposomes, 375, 389 bath sonication, 392 dialysis Method, 375, 395, 396 freeze-drying Method, 396 gas-bubbling Method, 397 hand-Shaken Multilamellar Vesicles, 375, 390 mechanical Dispersion Methods, 375, 389, 390 organic Solvent Dilution Method, 375, 395 pH-Gradient Method, 397 probe sonication, 392 size reduction mmbuat sonication, 392 Process analytical technology, 578 Process optimization, 637, 651, membuqt, 657 Prodrug, 437459 Promoiety, 437, 449442, 445448, 451, 453, 457458 Properties of Negatively Charged Phospholipids, fara, 384 Propylene glycol, 163, 166, 170189 Propylene glycol esters, 229 Proquazone, 570 Proton acceptor, 26 Proton donor, 26, 167 Prucalopride, 96, 99 Pseudopolymorph, 534 Pulsating nozzle, 594 PVP, 499, 505, 508, 510, 513, 516523 Q Quality by design (QbD), 104, 569 Quality control, 102105, 107, 111 Quantitative structure-solubility relationship, 31 R Radio frequency drying, 647 Ranitidine, 9596, 100 Rapidly dissolving, 103, 107 Forsx Jejunal perfusion, 61, 7778 Rate of reaction, 162, 170 Reaction rate, 168, 170 Reciprocating Die Process, 593 Recrystallization, 417, 421 Regression statistics, 34, 40, 51 Plate Process, 589590 Pluronics, 310, 314, 319, 322324, 347348, 353, 362 Polar, 2526, 3234, 40 Polarity, 32, 40, 5253 Poloxamers, 318, 324, 353354 Poly (ethylene oxide), 314, 318319, 350 Poly (l-amino acid), 310 Poly (N-isopropylacrylamide), 310, 343344, 354 Poly (propylene oxide), 318319 Polyelectrolyte, 324, 327, 422 Polyethylene glycol 400, 180 Polymer, 441, 442 Polymeric fore, 311, 334335, 346, 356, 358362 Polymeric salts, 422 Polymerized and uorinated liposomes, 375, 386 182 R (poly-PR) represents the difference in log P values between the given compound and the unsubstituted pyrazine, X is any substituent on the four available positions, and K ( 1J-PR) is the value calculated with the use of one of the correlation Eqs 23, 25 and 27.

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